Mignolet started out with his hometown club in Belgium, Sint-Truiden, making over 100 appearances in five years as the club climbed into the Belgian top flight.
In his final year at the club, 2009-10, he was voted Goalkeeper of the Year in his homeland and his form brought him to the attention of PSV Eindhoven, FC Twente and Udinese. He instead opted for a move to the Premier League, joining Sunderland for a reported £2m in June 2010.
Simon made his debut that August against Birmingham City, picking up the Man of the Match award in the process, and put in further sterling performances against Manchester City and Arsenal as he vied with Craig Gordon for a starting place.
Having seen off the Scot, Mignolet established himself as first-choice keeper and although he spent some time out of the side in 2011-12 due to facial injuries sustained in a collision with Aston Villa’s Emile Heskey, he returned to the side to keep three consecutive clean sheets – the first time Sunderland had achieved the feat since 2008.
Simon’s excellent form in the opening half of 2012-13 led England keeper Joe Hart to call him the best keeper in the league so far that season, and he lived up to the billing with a fine display in a 1-0 win against the Premier League champions.
Mignolet was also voted the 2012 North East Football Writers’ Association Player of the Year and has maintained his position in the team under new Sunderland boss Paolo Di Canio.
His form led to a bid from Liverpool boss Brendan Rodgers in the summer of 2013 and he joined the Reds in a £9m five-year deal, making his debut in a pre-season friendly at Preston North End.
He went on to play an integral role in the Reds' Premier League title challenge in 2013-14, helping the side reclaim their place in the Champions League.
Mignolet kept more clean sheets than any other Premier League goalkeeper in 2015 and he enjoyed another successful season between the posts following the arrival of Jurgen Klopp as boss, appearing in both the League Cup and Europa League finals, against Manchester City and Sevilla respectively, in 2015/16.
He continued his consistent form in 2016-17, firmly estabishing himself as first-choice as the Reds clinched a return to the Champions League.
Simon made his international debut in March 2011 in a 2-0 victory against Austria and was a member of Belgium's World Cup squad in Brazil and the 2016 Euros in France.